Mullins was 3-for-5, including a three-run homer and five RBIs as Baltimore outhit Toronto 14-4.

Tyler O'Neill also smashed a three-run blast in going 3-for-3 with two walks and Jordan Westburg added a solo homer for the Orioles. O'Neill has homered on Opening Day a record six consecutive seasons, adding to his major league record.

The six home runs were an Orioles' record for Opening Day.

Orioles starter Zach Eflin (1-0) gave up two runs and two hits in six innings, allowing Andres Gimenez's two-run homer. Toronto starter Jose Berrios (0-1) completed five innings, allowing six runs, nine hits and two walks.

Astros 3, Mets 1

Framber Valdez tossed seven shutout innings and Houston beat visiting New York.

Valdez scattered four hits, issued two walks and recorded four strikeouts. The Astros took a 3-0 lead in the third inning as Yainer Diaz hit an RBI single and Christian Walker scored on an error.

The Mets scored their run in the ninth on a sacrifice fly by Francisco Lindor. Juan Soto, the prized free-agent signing, went 1-for-3 with two walks in his Mets debut. Clay Holmes, a converted reliever making his first start since 2018, allowed three runs (two earned) on five hits and four walks with four strikeouts over 4 2/3 innings.

Padres 7, Braves 4

Jackson Merrill knocked in four runs and Gavin Sheets homered to spark a four-run seventh inning that allowed San Diego to rally for a win over visiting Atlanta.

San Diego's bullpen shouldered 6 1/3 innings of work after Michael King struggled in his 2 2/3 innings, giving up three runs on four hits and four walks. Wandy Peralta (1-0) got the last out of the top of the seventh to earn the win, and Robert Suarez closed it out in the ninth for the save.

Ozzie Albies drove in three runs, two on a home run, for Atlanta. Austin Riley also homered. Braves starter Chris Sale left with a 4-3 lead after yielding six hits, a walk and three runs in five innings, striking out seven.

White Sox 8, Angels 1

Rookie right-hander Sean Burke pitched six scoreless innings in his first Opening Day start and Austin Slater, Andrew Benintendi and Lenyn Sosa homered as host Chicago routed Los Angeles.

Burke (1-0) became the seventh pitcher since 1929 to make an Opening Day start with fewer than 20 career innings pitched. He retired the final 14 Angels he faced while giving up three hits and three walks and hitting one batter. Miguel Vargas hit a two-run double, Benintendi drove in three with his eighth-inning homer and Sosa hit a two-run shot in the eighth.

The Angels' Yusei Kikuchi (0-1) scattered three runs and five hits with five strikeouts over six innings. Los Angeles avoided the shutout in the ninth on Logan O'Hoppe's two-out, two-strike solo homer against Cam Booser.

Giants 6, Reds 4

Patrick Bailey singled home the tying run with two outs in the ninth inning and Wilmer Flores broke the tie one batter later with a three-run homer as San Francisco rallied to win a season opener in Cincinnati.

Heliot Ramos hit a two-run homer for the Giants. Starting pitcher Logan Webb was charged with three runs on six hits over five innings, striking out five and walking three.

Jeimer Candelario singled twice and drove three runs for the Reds. Starting pitcher Hunter Greene struck out eight in five innings. He allowed three hits and two runs, striking out eight and walking one on 84 pitches.

Yankees 4, Brewers 2

Carlos Rodon pitched effectively into the sixth inning and was backed by two early homers as host New York hung on for a victory over Milwaukee.

Austin Wells hit a leadoff homer three pitches into the home half of the first inning and Anthony Volpe connected in the second as the Yankees improved to 7-1 in season openers under manager Aaron Boone. Aaron Judge added an RBI double in the seventh and Cody Bellinger followed that at-bat with a sacrifice fly in his Yankees debut.

Vinny Capra, in his 21st career game, hit his first homer in the third. The Brewers, however, struck out 13 times. Leadoff batter Jackson Chourio struck out five times.

Red Sox 5, Rangers 2

Wilyer Abreu went 3-for-3 with two home runs, four RBIs and three runs scored as Boston earned a win over host Texas. The top slugger among American League rookies last season, Abreu homered in the fifth and ninth innings to lead the Red Sox to their second straight season-opening victory.

Abreu's second round-tripper broke a 2-2 tie in the ninth, coming after Trevor Story drew a one-out walk and stole second before highly rated prospect Kristian Campbell recorded his first MLB hit on a line single to third base. David Hamilton pinch ran for Campbell before the deciding swing.

Josh Jung and Kevin Pillar each had multiple hits for Texas, while the Red Sox won late after recording two runs on three hits and striking out nine times across Texas starter Nathan Eovaldi's six-inning start.

Phillies 7, Nationals 3 (10 innings)

Alec Bohm smacked a tiebreaking two-run double in the top of the 10th inning and the visiting Philadelphia went on to beat Washington on Opening Day.

With two outs in the 10th inning of a 3-3 game, runner Bryson Stott stole third and Bryce Harper walked against Colin Poche (0-1). Bohm then lined a double into the gap in left-center to score both runners, and JT Realmuto added a two-run triple to make it 7-3.

Harper and Kyle Schwarber hit seventh-inning solo home runs for the Phillies. Keibert Ruiz had two hits, including a homer, for the Nationals. Zack Wheeler allowed a run on two hits over six innings, striking out eight and walking two. MacKenzie Gore tossed six innings of one-hit ball and struck out 13 for a new Nationals Opening Day record.

Guardians 7, Royals 4 (10 innings)

Kyle Manzardo was 3-for-4 with a homer and four RBIs for Cleveland, which overcame a blown save by All-Star closer Emmanuel Clase to beat host Kansas City in an Opening Day clash.

Steven Kwan led off the 10th with the tiebreaking RBI double for the Guardians, who also got a two-run double in the inning from Manzardo. Manzardo began the comeback from a 3-0 deficit in the fourth, when he tripled and scored on a sacrifice fly by Jhonkensy Noel.

Vinnie Pasquantino hit a three-run homer in the third before he began the Royals' comeback by lacing a leadoff double against Clase (1-0) in the ninth. Salvador Perez followed with a single to send pinch runner Freddy Fermin to third before Fermin trotted home on Michael Massey's sacrifice fly.

Marlins 5, Pirates 4

Catcher Nick Fortes tripled to lead off the bottom of the ninth, and Kyle Stowers drilled a no-out, line-drive single down the right-field line as host Miami rallied for a walk-off win over Pittsburgh in the opener for both squads.

It was Miami's first walk-off victory on Opening Day. After Fortes' first triple since 2022, Stowers then hit the winner off closer David Bednar (0-1). Marlins reliever Jesus Tinoco (1-0) earned the win with a scoreless top of the ninth. Sandy Alcantara, who missed the 2024 season, allowed two hits, two runs and four walks in 4 2/3 innings, striking out seven.

Pittsburgh's biggest offensive plays were Bryan Reynolds' two-run single in the fifth and Nick Gonzales' two-run homer in the sixth. Paul Skenes, the reigning National League Rookie of the Year, allowed three hits, two walks and two runs and struck out seven in 5 1/3 innings.

Dodgers 5, Tigers 4

Shohei Ohtani, Teoscar Hernandez and Tommy Edman hit home runs, Blake Snell went five strong innings and defending champion Los Angeles capped a day of celebration with a victory over visiting Detroit.

In his Dodgers debut, the free-agent addition Snell (1-0) gave up two runs on five hits over five innings with two strikeouts. The two-time Cy Young Award winner was able to work around four walks. Blake Treinen pitched a scoreless ninth for his first save.

In his first start since winning the American League Cy Young Award last season, Tigers left-hander Tarik Skubal (0-1) gave up four runs on six hits over five innings with a walk and two strikeouts. Spencer Torkelson hit a home run with four walks for Detroit, while Manuel Margot had a sacrifice fly in his Detroit debut.

Cardinals 5, Twins 3

Lars Nootbaar hit a two-run homer and scored twice to lead St. Louis to a season-opening victory over visiting Minnesota.

Nolan Arenado hit a solo homer and Brendan Donovan went 2-for-4 with a run and an RBI for the Cardinals. Starter Sonny Gray (1-0) allowed two runs on four hits in five innings to earn the victory. Ryan Helsley, the sixth St. Louis pitcher, earned the save.

Minnesota starting pitcher Pablo Lopez (0-1) allowed four runs, two earned, on eight hits in five innings. Harrison Bader hit a two-run homer and Willi Castro hit an RBI double for the Twins.

Randy Arozarena also went deep for the Mariners and Tyler Soderstrom hit a pair of solo homers for the Athletics.

Soderstrom led off the eighth inning by lining a first-pitch, hanging slider from reliever Trent Thornton just over the right-field wall to give the A's a 2-1 lead.

The Mariners tied it with one out in the bottom of the inning on Arozarena's solo shot off the facade of the second deck in left field against Jose Leclerc. Following a walk to Luke Raley, Polanco deposited Leclerc's fastball over the wall in center field to give Seattle its first lead.

Thornton got the victory and Andres Munoz worked the ninth for the save.

For the most part, the opener was a pitching duel between right-handers Luis Severino and Logan Gilbert.

Severino spent the first nine seasons of his career in New York - eight with the Yankees and last year with the Mets - before signing with the A's in the offseason. On Thursday, he threw six scoreless innings and allowed three hits, walked four and struck out six.

Soderstrom broke a scoreless tie with one out in the fifth inning, hammering a hanging slider from Gilbert 432 feet over the fence in straightaway center field.

That was the lone mistake by Gilbert, who was making his first Opening Day start. The right-hander allowed just two hits over seven innings, with no walks and eight strikeouts.

The Mariners put runners on base in each of the first six innings against Severino but weren't able to convert.

They finally broke through against reliever Tyler Ferguson in the seventh, tying the score without the benefit of a base hit.

Ryan Bliss and J.P. Crawford led off with walks and Victor Robles squared around to bunt. Robles missed the ball, as did A's catcher Shea Langeliers, with the ball rolling to the backstop.

Bliss tried to score from second and was originally ruled safe, but a video review determined his lead foot bounced off the dirt and didn't touch the plate while Ferguson applied the tag. Crawford took third on the play and scored on Robles' sacrifice fly to center.

Ian Happ had two hits, including a homer, and drove in three runs. Left-hander Justin Steele (1-1) gave up three runs, with one walk and two strikeouts, in five innings to rebound from a season-opening loss to the Los Angeles Dodgers in the Tokyo Series on March 19.

Cubs second baseman Nico Hoerner had two hits and an RBI in his return to the lineup after missing the Tokyo trip while recovering from offseason forearm surgery.

Eugenio Suarez homered, Ketel Marte and Gabriel Moreno had two hits, and Geraldo Perdomo drove in two runs for the Diamondbacks.

The Cubs' first eight runs scored with two outs before Amaya's two-run double with one out in the ninth inning.

Arizona starter Zac Gallen (0-1) gave up four runs on four hits and four walks in four innings.

The Diamondbacks opened the scoring in the first inning, when leadoff hitter Marte doubled and scored on a two-out single by Josh Naylor. It was their only lead.

Gallen walked Pete Crow-Armstrong and Matt Shaw in the second, and Happ drove in both with a double. Kyle Tucker followed with a run-scoring single for a 3-1 lead.

Suarez hit a homer in the second before Happ's homer in the fourth gave the Cubs a 4-2 lead. Perdomo beat out a chopper to third to drive in Moreno in the fourth to make it 4-3.

Amaya's bases-clearing double off reliever Ryne Nelson in the fifth inning made it 7-3. Arizona center fielder Jake McCarthy reached Amaya's line drive with a dive, but the ball bounced out of his glove.

Crow-Armstrong, running from first, had extended the fifth inning when he beat the throw to second base on a routine grounder by Matt Shaw to shortstop Perdomo, loading the bases. Amaya followed with his hit.

In the sixth, Hoerner singled in a run before the Diamondbacks closed to 8-5, scoring on two sacrifice flies after Nate Pearson walked two and hit a batter.

In his Dodgers debut, the free-agent addition Snell (1-0) gave up two runs on five hits over five innings with two strikeouts. The two-time Cy Young Award winner was able to work around four walks. Blake Treinen pitched a scoreless ninth for his first save.

Ohtani hit his second home run in the third game of the season as the Dodgers played at home for the first time since a victory in Game 2 of the 2024 World Series against the New York Yankees.

In his first start since winning the American League Cy Young Award last season, Tigers left-hander Tarik Skubal (0-1) gave up four runs on six hits over five innings with a walk and two strikeouts. Spencer Torkelson hit a home run with four walks for Detroit, while Manuel Margot had a sacrifice fly in his Detroit debut.

Edman, the MVP of the NLCS last season, gave the Dodgers a 1-0 lead in the second inning with his homer. The Tigers tied the game when Torkelson scored in the fourth on a Snell wild pitch. Margot's sacrifice fly put Detroit up 2-1 in the fifth.

The Dodgers answered in the bottom of the fifth, getting a single from Andy Pages and a walk from Mookie Betts. Hernandez hit a two-out, first-pitch fastball from Skubal over the wall in center field for a 4-2 Los Angeles lead.

Torkelson's home run came in the top of the seventh before Ohtani responded with his homer in the bottom of the inning. Kerry Carpenter's sacrifice fly pulled Detroit within a run in the eighth.

The Tigers put two aboard with one out in the ninth before Treinen finished off the victory by striking out Trey Sweeney, then Colt Keith fouled out to first base.

The Tigers were facing their Dodgers to open the season for the first time in franchise history, while Los Angeles opened its home schedule against an American League club for the first time.

Nolan Arenado hit a solo homer and Brendan Donovan went 2-for-4 with a run and an RBI for the Cardinals.

Cardinals starter Sonny Gray (1-0) allowed two runs on four hits in five innings to earn the victory. Ryan Helsley, the sixth St. Louis pitcher, earned the save.

Harrison Bader hit a two-run homer and Willi Castro hit an RBI double for the Twins.

Minnesota starting pitcher Pablo Lopez (0-1) allowed four runs, two earned, on eight hits in five innings.

After rain delayed the start of the game for 1 hour, 38 minutes, the Cardinals took a 1-0 first-inning lead. Nootbaar hit a leadoff single, took second on a balk and scored on Donovan's single.

The Twins threatened in the second inning. Trevor Larnach hit a single and moved to third on Ty France's one-out single. Willi Castro walked to load the bases.

But Gray defused the threat by striking out Jose Miranda and retiring Bader on a popout.

St. Louis upped its lead to 3-0 in the bottom half of the inning with a single by Jordan Walker and Nootbaar's two-out, two-run homer.

Singles by Donovan, Nolan Arenado and Ivan Herrera increased the Cardinals' lead to 4-0 in the third inning.

The Twins cut their deficit to 4-2 in the fifth inning on a single by Miranda and Bader's two-run homer.

Minnesota trimmed it to 4-3 in the sixth inning off relievers Kyle Leahy and John King. Larnach walked with one out, Ryan Jeffers hit a single, and Castro hit a two-out RBI double.

Cardinals center fielder Victor Scott II prevented a much bigger inning by sprinting into the right-center field gap with one out to rob France of a potential RBI double.

Arenado's eighth-inning homer increased the Cardinals' lead to 5-3.

Playing in front of the largest Opening Day crowd in Petro Park's 22-season history - 45,568 - San Diego trailed 4-3 before victimizing Hector Neris (0-1) and the Atlanta bullpen. Sheets drilled a pinch-hit, 405-foot shot over the center-field wall to tie the game.

Elias Diaz and Fernando Tatis Jr. singled to put runners at the corners. Reliever Aaron Bummer came in and allowed the tiebreaking sacrifice fly to Luis Arraez, then an RBI double by Manny Machado. After an intentional walk to Xander Bogaerts, he and Machado orchestrated a double steal that preceded Merrill's sacrifice fly to cap the big inning.

Wandy Peralta (1-0) got the last out of the top of the seventh on one pitch to earn the win, and Robert Suarez closed it out in the ninth for the save. San Diego's bullpen shouldered 6 1/3 innings of work after Michael King struggled in his 2 2/3 innings.

Making his first Opening Day start, King was touched for three runs on four hits and four walks, fanning three and throwing 76 pitches. Braves starter Chris Sale left with a 4-3 lead after yielding six hits, a walk and three runs in five innings, striking out seven.

Atlanta initiated scoring in the first when Ozzie Albies reached on a fielder's choice with the bases loaded and one out, plating Jurickson Profar. Albies was originally called out but the call was overturned via replay review.

That lead didn't last long as Merrill poked a two-run, two-out, two-strike single into center in the bottom of the inning to score Tatis and Machado. Albies gave the Braves a 3-2 lead in the third, clouting a long two-run homer halfway up the seats in right.

Merrill tied it in the bottom of the inning with an RBI groundout but Austin Riley put Atlanta up 4-3 in the fourth with a homer to left-center.

It was Miami's first walk-off victory on Opening Day.

It was Fortes' first triple since 2022, and it was misplayed by center fielder Oneil Cruz, who played shortstop until last year. The ball hit the wall on the fly, and Cruz could have held Fortes to a double, but the outfielder got too close to the fence and the ball rolled past him.

Stowers then hit the winner off of closer David Bednar (0-1).

Marlins reliever Jesus Tinoco earned the win with a scoreless top of the ninth.

Pittsburgh's biggest offensive plays were Bryan Reynolds' two-run single in the fifth inning and Nick Gonzales' two-run homer in the sixth.

Gonzales appeared to hurt his left foot while rounding the bases in the sixth, and he left the game the following inning.

Both teams pitched their aces, but neither one earned a decision.

Pittsburgh's Paul Skenes, the reigning National League Rookie of the Year, allowed three hits, two walks and two runs in 5 1/3 innings. He struck out seven.

At age 22, he became the youngest Opening Day starting pitcher in Pirates history.

Alcantara, who won the NL's Cy Young Award in 2022, allowed two hits, two runs and four walks in 4 2/3 innings, striking out seven.

Following elbow surgery late in the 2023 season, this was his first MLB regular-season appearance in 571 days.

Miami got its first hit in the third as Derek Hill hit a double that one-hopped the wall in left.

The Marlins then hustled to get a 1-0 lead as Graham Pauley beat out an infield single, and Xavier Edwards hit an RBI groundout. In between those plays, Fortes hustled to keep from bouncing into a double play, and that allowed Hill to get to third.

Pittsburgh got its first hit with two outs in the fifth as Ke'Bryan Hayes singled. Alcantara walked the next two batters, and Reynolds stroked his two-run single on a ground ball to center.

The Pirates stretched their lead to 4-1 in the sixth as Joey Bart was hit by a pitch, and Gonzales made it 4-1 on his two-run homer to left.

Skenes walked two of the first three batters in the bottom of the sixth, and he was removed. Reliever Dennis Santana then walked Jonah Bride, and Edwards scored on a passed ball charged to Bart.

Miami tied the score 4-4 in the eighth against reliever Colin Holerman, who walked leadoff batter Stowers. The Marlins then got two-out RBI singles from Otto Lopez and Dane Myers.

The top slugger among American League rookies last season, Abreu homered in the fifth and ninth innings to lead the Red Sox to their second straight season-opening victory.

Abreu's second round-tripper broke a 2-2 tie in the ninth, coming after Trevor Story drew a one-out walk and stole second before highly rated prospect Kristian Campbell recorded his first MLB hit on a line single to third base. David Hamilton pinch ran for Campbell before the deciding swing.

The Boston bullpen -- Garrett Whitlock, Aroldis Chapman (1-0) and Justin Slaten -- allowed just two hits over a combined four scoreless innings in relief of Garrett Crochet. Slaten pitched a 1-2-3 ninth with a strikeout for the save.

Josh Jung and Kevin Pillar each had multiple hits for Texas.

The Red Sox won late after recording two runs on three hits and striking out nine times across Texas starter Nathan Eovaldi's six-inning start. Luke Jackson (0-1) took the loss.

A leadoff walk to Jake Burger bit Crochet in the bottom of the second, as back-to-back singles from Jung and Pillar followed to lift Texas to an early lead. Pillar's liner through the middle drove home the opening run from second base.

After Eovaldi struck out the side in his second of two opening 1-2-3 innings, Boston quickly generated the tying run in the third. Consecutive knocks by Abreu and Connor Wong set up runners on the corners, and Ceddanne Rafaela's fielder's choice grounder to short followed to make it 1-1.

Crochet set down eight Rangers in a row after surrendering the first run, but the hosts climbed back in front in the fourth after Pillar extended the inning with a two-run single and scored on Higashioka's deep double over the head of Rafaela in center field.

Crochet departed after five innings of two-run ball, allowing five hits and two walks while striking out five in his Red Sox debut.

One swing of the bat in the Boston fifth broke Eovaldi's streak of six straight batters retired following the Rafaela RBI, as Abreu crushed a one-out homer to right to tie the game at 2.

Before rallying to win, Boston left two runners stranded after Chris Martin came on to strike out Wong in the seventh.

Jarren Duran singled and reached third in the eighth, but Alex Bregman, who went 0-for-4 in his Red Sox debut, lined out to end the inning.

Valdez (1-0) became the first left-hander in franchise history to make four consecutive Opening Day starts. He scattered four hits, issued two walks and recorded four strikeouts, seemingly strengthening as he worked deeper into his outing. Valdez tossed 90 pitches, 56 for strikes.

He faced trouble in the top of the first when he surrendered a one-out single to Juan Soto before Pete Alonso walked. Valdez recovered and retired Mark Vientos and Brandon Nimmo in succession and didn't allow another hit until Luis Torrens doubled with one out in the fifth.

Torrens was subsequently erased trying to advance to third base for the final out of that frame.

Valdez induced eight groundball outs, including a double-play grounder by Vientos to close the sixth. Valdez entered the seventh with 81 pitches on his ledger, and after Nimmo reached with a leadoff single, Valdez recorded strikeouts of Starling Marte and Luisangel Acuna to cap his day.

Infielders Isaac Paredes, Christian Walker, Brendan Rodgers and rookie right fielder Cam Smith made their Astros debuts. Smith dumped an opposite-field single into right field in his first career at-bat for the lone hit in the bottom of the second. Jeremy Pena (hit by pitch) and Rodgers (walk) reached bracketing Smith, and Pena scored when Jake Meyers delivered a run-scoring fielder's choice.

Paredes walked and scored in the Astros' two-run third when Yainer Diaz produced an RBI single to center off Mets right-hander Clay Holmes (0-1). Walker singled and later scored when second baseman Acuna committed a throwing error on a fielder's choice grounder from Pena.

Holmes, a converted reliever making his first start since 2018, allowed three runs (two earned) on five hits and four walks with four strikeouts over 4 2/3 innings.

Soto, the prized free-agent signing who played last season for the New York Yankees, went 1-for-3 with two walks in his Mets debut. He struck out representing the go-ahead run in the ninth against Astros closer Josh Hader, who loaded the bases with no outs and allowed a run-scoring sacrifice fly to Francisco Lindor.

The Mets loaded the bases with two outs against Astros reliever Bryan Abreu in the eighth, but Nimmo was retired on a flyout to center.

Steven Kwan led off the 10th inning with the tie-breaking RBI double for the defending American League Central champion Guardians, who have won both their season openers under second-year manager Stephen Vogt.

Manzardo began the Guardians' comeback from a 3-0 deficit in the fourth, when he tripled and scored on a sacrifice fly by Jhonkensy Noel. Jose Ramirez lofted another sacrifice fly in the fifth before Manzardo greeted Angel Zerpa by hitting a two-run homer on the first pitch he saw in the sixth.

The 24-year-old, who made his first Opening Day roster this season, added insurance with a two-out, two-run double off Sam Long (0-1) in the 10th.

Paul Sewald earned the save with a perfect 10th.

Kwan had two hits.

Vinnie Pasquantino, who was questionable entering the game due to a right hamstring injury he suffered last Saturday, hit a three-run homer in the third before he began the Royals' comeback by lacing a leadoff double against Clase (1-0) in the ninth.

Salvador Perez followed with a single to send pinch-runner Freddy Fermin to third before Fermin trotted home on Michael Massey's sacrifice fly to the track in right.

Clase was 47-of-49 in regular season save opportunities last season, when he posted an 0.61 ERA and finished third in the American League Cy Young Award balloting, before he went 0-2 with a 9.00 ERA and two saves in three chances over seven playoff appearances.

Pasquantino was the only player with multiple hits for the Royals, who fell to 0-3 on Opening Day under manager Matt Quatraro.

Neither starter factored into the decision after five-inning outings.

The Guardians' Ben Lively, who was pressed into duty when Tanner Bibee was scratched due to food poisoning, gave up three runs on four hits and no walks while striking out three. The Royals' Cole Ragans allowed three runs on five hits and two walks while whiffing three.

With two outs in the tenth inning of a 3-3 game, runner Bryson Stott stole third and Bryce Harper walked against Colin Poche (0-1). Bohm then lined a double into the gap in left center to score both runners, and JT Realmuto added a two-run triple to make it 7-3.

Harper and Kyle Schwarber hit seventh-inning solo home runs for the defending NL East-champion Phillies.

Jose Alvarado (1-0) pitched a scoreless ninth for the win.

Keibert Ruiz had two hits, including a homer, for the Nationals.

Philadelphia starter Zack Wheeler allowed a run on two hits over six innings. He struck out eight and walked two.

Washington got a stellar start from left-hander MacKenzie Gore in his first opener. The 26-year-old tossed six innings of one-hit baseball, didn't walk a batter, and struck out 13 for a new Nationals Opening Day record.

With Washington trailing 3-1, Dylan Crews walked leading off the eighth against Jordan Romano and Jacob Young was hit by a pitch. After a double steal, CJ Abrams grounded softly to first, scoring Crews. James Wood struck out, but Luis Garcia, Jr. blooped a single to center to tie it.

Schwarber singled leading off the second for the only hit off Gore.

In the fifth, Ruiz capped a 12-pitch at-bat against Wheeler when he homered into the Nationals bullpen in right.

Manager Rob Thomson's altered batting order -- with Trea Turner leading off and Schwarber batting fourth instead of leading off against a lefty starter -- paid off against the Washington bullpen in the seventh.

With one out, Harper homered to center off right-handed reliever Lucas Sims. With two outs, lefty Jose A. Ferrer came on to face Schwarber, who homered to right center on the first pitch.

In the Philadelphia eighth, Max Kepler doubled and Nick Castellanos singled him to third. Ferrer struck out Stott and Brandon Marsh, but then uncorked a wild pitch to Turner that allowed Kepler to score, making it 3-1.

Chicago, which lost a major league single-season record 121 games last season, treated the Guaranteed Rate Field crowd to a crisp effort. The White Sox outhit the Angels 9-5 while Burke outpitched Los Angeles lefty Yusei Kikuchi.

Burke (1-0) appeared in four games in September and became the seventh pitcher since 1929 to make an opening day start with fewer than 20 career innings pitched. He retired the final 14 Angels he faced while spacing three hits, three walks and one hit batsman.

Taylor Ward led off the game with a double. Los Angeles later had two men in scoring position with one out before Burke escaped the jam by retiring Jorge Soler on a swinging strikeout and getting Tim Anderson looking. After throwing 24 pitches in the first inning, Burke needed no more than 11 pitches to complete any of the rest of his innings.

Slater smacked a home run to left field leading off the second in his first at-bat with the White Sox. In a matchup of offseason acquisitions, he took Kikuchi deep on a 2-1 pitch.

Chicago surged ahead 3-0 with two outs in the inning as Miguel Vargas blooped a hustling, two-run double to short left field.

Kikuchi (0-1) regrouped to set down the last 13 White Sox he faced. He scattered three runs and five hits with five strikeouts over six innings.

The Angels loaded the bases with two outs in the eighth but Mike Clevinger fanned Soler to end the threat.

Angels righty Ryan Johnson, a 2024 draft pick who didn't throw a pitch in the minors last season, worked a 1-2-3 seventh in his major league debut. He encountered trouble in the eighth, however, surrendering a three-run shot to Benintendi and a two-run blast to Sosa.

Los Angeles avoided the shutout in the ninth on Logan O'Hoppe's two-out, two-strike solo shot against Cam Booser.

O'Hoppe and Vargas had two hits apiece.

Angels right fielder Mike Trout was hit on the hand by a pitch in his first plate appearance but remained in the game, going 0-for-2 with a walk.

Tyler Rogers (1-0) pitched a scoreless eighth for the win. Ryan Walker gave up a run-scoring single to TJ Friedl before retiring Matt McLain on a fly ball just short of the wall in left to record the save.

Jeimer Candelario singled twice and drove in all three Cincinnati runs while starting pitcher Hunter Greene struck out eight in five innings to stake the Reds to an early 3-0 lead.

Scott Barlow, Emilio Pagan and Tony Santillan combined to throw a scoreless inning apiece before Ian Gibaut came on for the save in the ninth but ran into a jam that he could escape after first-and-third with one out.

Gibaut (0-1) gave up the game-tying two-out single and the go-ahead homer and was charged with all four runs in the San Francisco ninth.

Cincinnati pitchers combined to strike out 17 San Francisco batters and allowed six hits in the loss.

Bailey's two-out single in the ninth scored Jung Hoo Lee and tied the game, 3-3, before Flores launched the go-ahead shot to the seats in left.

Greene opened in overpowering form, striking out five of the first six batters he faced and retiring the first seven batters before Mike Yastrzemski lined a solid single to center with one out in the third. Greene allowed three hits and two runs over five innings, striking out eight and walking one on 84 pitches.

Giants starter Logan Webb was charged with three runs on six hits over his five innings, striking out five and walking three.

Heliot Ramos fouled off five straight pitches from Greene before driving the 11th pitch of the at-bat -- a fastball -- over the wall in right for a two-run homer that cut Cincinnati's lead to 3-2 in the fourth inning. The ball landed in the first row of seats just beyond the reach of right fielder Jake Fraley.

The Reds and Giants, whose rivalry dates to the late 1800s, were meeting for just the fourth time on Opening Day. The Giants have won all four.

Weather conditions were not a major factor for Thursday's game, the earliest calendar date opener for both clubs. The game-time temperature was 61 degrees under cloudy skies.

O'Neill's blast to right field came against right-hander Jose Berrios of the Toronto Blue Jays and gave Baltimore a 5-0 lead.

O'Neill's streak began in 2020 with St. Louis, the first of four straight Opening Day blasts with the Cardinals. Last season, he homered for the Boston Red Sox on Opening Day.

Last season's homer allowed O'Neill to surpass the previous record of four straight Opening Day homers, shared by Yogi Berra (1955-58), Gary Carter (1977-80) and Todd Hundley (1994-97).

O'Neill was 3-for-3 with three runs, three RBIs and a walk through seven innings of Thursday's game in Toronto.

Mullins was 3-for-5, including a three-run homer and five RBIs as Baltimore outhit Toronto 14-4.

Tyler O'Neill also smashed a three-run blast in going 3-for-3 with two walks and Jordan Westburg added a solo homer for the Orioles to begin the four-game series.

The six home runs were an Orioles' record for Opening Day.

O'Neill has homered on Opening Day a record six consecutive seasons. He also threw out a runner trying for a double in the ninth.

Orioles starter Zach Eflin (1-0) gave up two runs and two hits in six innings, allowing Andres Gimenez's two-run homer.

Toronto starter Jose Berrios (0-1) was falling behind in the count early in his third Opening Day start for Toronto. It hurt him when Rutschman hit a 2-1 changeup to right center for a home run with one out in the first.

A leadoff walk to O'Neill in the second led to another Orioles run. He took third on Ryan Mountcastle's double to left and scored when Mullins beat out an infield single on a high chopper to first.

A leadoff walk to Colton Cowser led to a three-run Orioles third. Rutschman singled and, with two out, O'Neill drilled a homer to right on a 2-1 sinker.

Mullins hit the first pitch of the fourth inning for a homer to right center to make it 6-0.

Toronto's first hit was Gimenez's homer into the Baltimore bullpen in right field with two out in the home fourth. It scored Vladimir Guerrero Jr., who had walked.

Berrios completed five innings, allowing six runs, nine hits and two walks.

Alan Roden led off the Toronto sixth by bouncing a single up the middle for his first major-league hit. He also had a walk.

Baltimore took a 9-2 lead in the seventh. Jacob Barnes allowed a walk and a single. Chad Green took over with two out and allowed Mullins' homer, a blast to right center.

Yariel Rodriguez allowed Rutschman's two-run homer and Westburg's solo shot in the eighth that brought loud boos from the Toronto fans.

Former Oriole Anthony Santander was 0-for-4 in his first game for the Blue Jays.

Austin Wells hit a leadoff homer three pitches into the home half of the first inning and Anthony Volpe connected in the second as the Yankees improved to 7-1 in season openers under manager Aaron Boone. Aaron Judge added an RBI double in the seventh and Cody Bellinger followed that at-bat with a sacrifice fly in his Yankees debut. Those runs proved crucial when New York's new closer, Devin Williams, struggled in the ninth against his former team.

Starting the third season of a six-year, $162 million deal, Rodon (1-0) allowed one run on four hits in 5 1/3 innings. The left-hander struck out seven and walked two in his second career Opening Day start.

Vinny Capra, in his 21st career game, hit his first homer in the third. The Brewers, however, struck out 13 times. Leadoff batter Jackson Chourio struck out five times, including against Williams in the ninth.

Milwaukee's Freddy Peralta (0-1) allowed two runs on four hits in five innings during his second career Opening Day start.

After shining through spring training as the rare catcher to bat leadoff, Wells gave the Yankees the lead by blasting a 2-0 fastball into the right-center field seats. It was the leadoff homer by a Yankee on Opening Day, according to MLB.com researcher Sarah Langs.

Volpe made it 2-0 by driving a 1-1 fastball to right-center with two outs in the second, and the Yankees added two in the seventh off Jared Koenig. Judge hit a double that caromed off the third-base bag into left field, and Oswaldo Cabrera scored on Bellinger's fly ball after third base coach Luis Rojas appeared to put a stop sign.

Rodon exited with two on in the sixth after issuing a walk to Rhys Hoskins on a close pitch. Tim Hill left the bases loaded in the sixth, Mark Leiter Jr. pitched a 1-2-3 seventh and Luke Weaver protected the three-run lead in the eighth.

Williams, a two-time All-Star, was acquired by New York in the offseason for left-hander Nestor Cortes. Williams loaded the bases with nobody out in his debut in the ninth.

He opened his outing by allowing a single to Joey Ortiz and a double to Issac Collins before walking pinch hitter Jake Bauers. After Bauers walked, right-hander Fernando Cruz began warming up and Williams allowed a sacrifice fly to Brice Turang.

Williams whiffed Chourio and ended the game by fanning Christian Yelich.

Problems reportedly began during the streaming of the day's two earliest games -- the Milwaukee Brewers at the New York Yankees and the Baltimore Orioles at the Toronto Blue Jays -- with the games cutting off. Nine more games started in the 4 p.m. ET hour, and viewers were met with an error message that instructed them to try again later.

Users reported the service was up and running around 4:40p.m. but that was no consolation to fans who waited all winter for March 27 and wanted to experience the pageantry of Opening Day from the start.

"Took a day of PTO and the MLB.TV doesn't work for opening day. Terrrrrrible look and such a disappointment for a product I pay $150 for," subscriber Ben Fawcett (@benjaminfawcett) wrote on X.

The timing of the outage -- aside from Opening Day -- couldn't have been worse for Major League Baseball, which said last month it no longer will partner with ESPN after this season. One of the reasons given was the increased interest from streaming companies, and that wasn't lost on at least one fan.

"@MLB wants to ditch @ESPN and move to streaming, so naturally mlb.tv is COMPLETELY DOWN ON OPENING DAY. Karma," wrote Doug Hardy (@doughardy31) on X.

Variety reported that as of 4:03 p.m. ET Thursday, more than 21,000 complaints had been made on the monitoring service Downdetector.com.

There was no explanation about the outage on the MLB's website, but there was an article letting fans know they could buy MLB.tv for $149.99 a season.

Moniak, 26, was released by the Los Angeles Angels on Tuesday following 2 1/2 seasons with the club.

According to multiple reports, Moniak's deal is worth $1.25 million.

Over five seasons, Moniak is a .230 hitter with a .673 OPS, 32 home runs and 105 RBIs in 275 games with the Philadelphia Phillies (2020-22) and Angels. He was the first overall draft pick by the Phillies in 2016 and traded to the Angels in 2022 in the deal that sent right-hander Noah Syndergaard to Philadelphia.

Moniak displayed promise in 2023 when he batted .280 with 14 homers and 45 RBIs in 85 games for the Angels. But last season, his average dropped to .219 and he had 14 homers and 49 RBIs in a career-high 124 games.

With the Dodgers' 26-man roster already set for Thursday's season opener at home against the Detroit Tigers, Davis will open the season at Triple-A Oklahoma City.

To open a spot on the 40-man roster for Los Angeles, right-hander Emmet Sheehan (Tommy John) was transferred to the 60-day IL.

Davis, 27, has 18 games of major league experience (six starts), all with the Colorado Rockies over the previous three seasons. He has an 0-4 record with a 7.71 ERA in 51 1/3 innings.

Hendriks, 36, made seven appearances in spring training for the Red Sox but was placed on the IL among moves to finalize the Opening Day roster in advance of Thursday's road game against the Texas Rangers.

In 2023, Hendriks made a triumphant return to the Chicago White Sox from a bout with non-Hodgkin lymphoma but after five outings, he was diagnosed with an elbow injury that required Tommy John surgery. He missed the entire 2024 season.

The Australia native signed a two-year, $10-million deal with the Red Sox in February 2024, despite the injury.

A three-time All-Star, Hendriks is 33-34 with a 3.82 ERA in 476 appearances (44 starts) for five franchises since 2011.

In other Red Sox moves to finalize their 26-man roster, left-handers Chris Murphy and Zach Penrod both were placed on the 60-day IL with elbow injuries, while outfielder Masataka Yoshida was sent to the 10-day IL after shoulder surgery in the offseason.

Right-handers Lucas Giolito (hamstring), Brayan Bello (shoulder) and Kutter Crawford (knee) all were placed on the 15-day IL. Right-handed reliever Cooper Criswell, 28, was named to Boston's Opening Day roster.